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Carsten Müller-Tidow Selected Research

promyelocytic leukemia-retinoic acid receptor alpha fusion oncoprotein

6/2010Pim2 cooperates with PML-RARalpha to induce acute myeloid leukemia in a bone marrow transplantation model.
3/2008Chromatin modifications induced by PML-RARalpha repress critical targets in leukemogenesis as analyzed by ChIP-Chip.
11/2006Proteomic analysis of acute promyelocytic leukemia: PML-RARalpha leads to decreased phosphorylation of OP18 at serine 63.
12/2004The serine-threonine kinase MNK1 is post-translationally stabilized by PML-RARalpha and regulates differentiation of hematopoietic cells.

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Carsten Müller-Tidow Research Topics

Disease

89Neoplasms (Cancer)
05/2022 - 07/2002
81Acute Myeloid Leukemia (Acute Myelogenous Leukemia)
06/2022 - 07/2002
39Leukemia
01/2022 - 07/2002
19Multiple Myeloma
01/2022 - 03/2006
15Non-Small-Cell Lung Carcinoma (Carcinoma, Non-Small Cell Lung)
01/2021 - 02/2003
14Neoplasm Metastasis (Metastasis)
01/2017 - 09/2003
10Graft vs Host Disease (Graft-Versus-Host Disease)
01/2022 - 04/2015
10Infections
04/2021 - 04/2005
9Acute Promyelocytic Leukemia
12/2021 - 11/2006
8B-Cell Lymphoma (Lymphoma, B Cell)
12/2021 - 12/2011
8Lung Neoplasms (Lung Cancer)
01/2021 - 09/2003
7Hematologic Neoplasms (Hematological Malignancy)
02/2022 - 08/2007
7Myelodysplastic Syndromes (Myelodysplastic Syndrome)
01/2021 - 08/2008
6Precursor Cell Lymphoblastic Leukemia-Lymphoma (Acute Lymphoblastic Leukemia)
04/2021 - 02/2007
5Sarcoma (Soft Tissue Sarcoma)
02/2022 - 06/2015
5Testicular Neoplasms (Testicular Cancer)
02/2022 - 02/2003
5Inflammation (Inflammations)
12/2020 - 12/2013
4Immunoglobulin Light-chain Amyloidosis
10/2021 - 11/2018
4Carcinogenesis
01/2021 - 02/2003
4B-Cell Chronic Lymphocytic Leukemia (Chronic Lymphocytic Leukemia)
01/2021 - 01/2017
4Ewing Sarcoma (Sarcoma, Ewing)
11/2017 - 11/2015
4Infarction (Infarctions)
01/2017 - 03/2013
4Carcinoma (Carcinomatosis)
01/2017 - 02/2003
4BCR-ABL Positive Chronic Myelogenous Leukemia (Chronic Myelogenous Leukemia)
02/2012 - 07/2003
3COVID-19
02/2022 - 10/2020
3Disease Progression
12/2021 - 12/2013
3Non-Hodgkin Lymphoma (Lymphosarcoma)
04/2021 - 01/2019
3Lymphoma (Lymphomas)
01/2020 - 12/2011
3Anemia
02/2018 - 06/2015
2Hypoxia (Hypoxemia)
01/2022 - 01/2017
2T-Cell Lymphoma (Lymphoma, T Cell)
01/2022 - 12/2021
2Sepsis (Septicemia)
01/2022 - 12/2014
2Bronchiolitis Obliterans Syndrome
10/2021 - 01/2021
2Residual Neoplasm
01/2021 - 02/2012
2Amyloidosis
01/2021 - 03/2018
2Lymphopenia (Lymphocytopenia)
10/2020 - 01/2013
2Body Weight (Weight, Body)
04/2020 - 11/2017
2Myeloid Leukemia (Leukemia, Myelocytic)
01/2020 - 12/2016

Drug/Important Bio-Agent (IBA)

31Proteins (Proteins, Gene)FDA Link
12/2021 - 07/2002
21Chimeric Antigen ReceptorsIBA
05/2022 - 01/2017
13Transcription Factors (Transcription Factor)IBA
01/2021 - 04/2004
12Messenger RNA (mRNA)IBA
01/2017 - 07/2002
12Phosphotransferases (Kinase)IBA
01/2016 - 02/2004
11Biomarkers (Surrogate Marker)IBA
01/2021 - 02/2007
10DNA (Deoxyribonucleic Acid)IBA
10/2021 - 02/2007
9Pharmaceutical PreparationsIBA
11/2021 - 02/2004
9Receptor Protein-Tyrosine Kinases (Tyrosine Kinase Receptors)IBA
01/2016 - 04/2003
8Cyclin A1IBA
01/2009 - 08/2002
7RNA (Ribonucleic Acid)IBA
01/2022 - 01/2017
7Tretinoin (Retinoic Acid)FDA LinkGeneric
12/2021 - 08/2008
7CytokinesIBA
10/2021 - 10/2004
7Protein-Tyrosine Kinases (Tyrosine Kinase)IBA
01/2012 - 03/2005
6ChromatinIBA
10/2021 - 03/2008
5AntigensIBA
02/2022 - 01/2012
5Small Interfering RNA (siRNA)IBA
01/2022 - 03/2008
5Azacitidine (5 Azacytidine)FDA Link
12/2021 - 01/2012
5Lenalidomide (CC 5013)FDA Link
10/2021 - 08/2008
5Cytarabine (Cytosar-U)FDA LinkGeneric
01/2021 - 01/2015
5tyrosine receptor (receptor, tyrosine)IBA
01/2016 - 02/2004
4SteroidsIBA
01/2022 - 01/2018
4Dexamethasone (Maxidex)FDA LinkGeneric
10/2021 - 01/2021
4Melphalan (Alkeran)FDA LinkGeneric
01/2021 - 09/2012
4AntibodiesIBA
01/2021 - 03/2015
4Thromboplastin (Tissue Factor)IBA
01/2017 - 03/2013
4LigandsIBA
01/2016 - 12/2006
4MicroRNAs (MicroRNA)IBA
04/2014 - 01/2008
4Imatinib Mesylate (Gleevec)FDA Link
03/2011 - 08/2008
4promyelocytic leukemia-retinoic acid receptor alpha fusion oncoproteinIBA
06/2010 - 12/2004
4CyclinsIBA
01/2009 - 09/2003
3Interleukin-6 (Interleukin 6)IBA
01/2022 - 10/2004
3venetoclaxIBA
01/2022 - 01/2020
3Immunomodulating AgentsIBA
01/2022 - 10/2018
3Tyrosine (L-Tyrosine)FDA Link
01/2021 - 01/2012
3MethyltransferasesIBA
12/2017 - 09/2013
3Cisplatin (Platino)FDA LinkGeneric
01/2017 - 03/2015
3Sorafenib (BAY 43-9006)FDA Link
12/2015 - 06/2012
3Type 1 Fibroblast Growth Factor Receptor (Fibroblast Growth Factor Receptor 1)IBA
11/2015 - 03/2005
3Rituximab (Mabthera)FDA Link
12/2013 - 04/2010
3CCAAT-Enhancer-Binding Protein-alphaIBA
08/2012 - 03/2010
3EphB6 ReceptorIBA
01/2012 - 07/2009
2LeptinIBA
02/2022 - 03/2018
2Histone Deacetylase InhibitorsIBA
02/2022 - 01/2020
2Immunoconjugates (Immunoconjugate)IBA
01/2022 - 01/2021
2EnzymesIBA
11/2021 - 09/2015
2Granulocyte Colony-Stimulating Factor (G-CSF)IBA
07/2021 - 11/2017
2daratumumabIBA
01/2021 - 01/2020
2Membrane Proteins (Integral Membrane Proteins)IBA
01/2021 - 03/2013
2Mycophenolic Acid (Cellcept)FDA LinkGeneric
04/2020 - 09/2016

Therapy/Procedure

50Therapeutics
06/2022 - 07/2003
25Drug Therapy (Chemotherapy)
09/2021 - 08/2004
23Stem Cell Transplantation
02/2022 - 09/2012
11Immunotherapy
02/2022 - 10/2004
5Homologous Transplantation
02/2022 - 07/2011
5Cell Transplantation
01/2022 - 07/2011
5Hematopoietic Stem Cell Transplantation
01/2020 - 01/2018
3Photopheresis
01/2022 - 01/2018
3Transplantation
01/2020 - 06/2010
2Aftercare (After-Treatment)
11/2021 - 12/2018
2Radiotherapy
10/2021 - 12/2005
2Antibiotic Prophylaxis
07/2021 - 10/2016